Pancreatic cancer is known as one of the deadliest forms of cancer, with a five-year survival rate of less than 10%. Often referred to as a “silent killer,” it shows few symptoms in its early stages, making it difficult to detect until it has progressed. The American Cancer Society projects that over 62,000 new cases will be diagnosed in the United States in 2024, with nearly 50,000 deaths. Early detection is critical, yet many people overlook the warning signs. This article highlights 10 common but often ignored symptoms of pancreatic cancer to help raise awareness.
One of the earliest signs is sudden, unexplained weight loss. According to the Mayo Clinic, this occurs because the cancer impairs the body’s ability to digest nutrients, leading to malnutrition. Unexpected weight loss, especially when paired with other symptoms like fatigue or changes in appetite, should always be investigated.
Another common symptom is jaundice, which presents as a yellowing of the skin and eyes. The American Cancer Society notes that jaundice can occur when a tumor blocks the bile duct, often without pain. This painless jaundice is easy to miss but can be a key indicator of pancreatic cancer. According to the Hindustan Times
Dark urine, a symptom of jaundice, can also be an early sign. Johns Hopkins Medicine explains that dark urine results from a buildup of bilirubin in the blood, which is a byproduct of the liver.
Stool changes, particularly light-colored or greasy stool, are often linked to pancreatic cancer. The American Cancer Society explains that when the bile duct is blocked, bile can’t reach the intestines, leading to changes in stool appearance. This symptom, although subtle, can signal digestive issues related to the disease.
Pancreatic cancer can also disrupt the pancreas’s ability to produce insulin, leading to new-onset diabetes. The CDC stresses that the sudden development of diabetes, particularly in people with no prior risk factors, should be closely monitored.
Persistent abdominal or back pain is another common but overlooked symptom. The Cleveland Clinic points out that this pain often results from a tumor pressing on surrounding organs or nerves. If the pain worsens over time, it’s important to seek medical attention. report from ACS.
Loss of appetite is a common early sign as well, as pancreatic cancer can disrupt digestion. According to the American Society of Clinical Oncology (ASCO), many patients report feeling full quickly or losing interest in eating altogether.
Nausea and vomiting are often dismissed as minor stomach issues, but the Pancreatic Cancer Action Network warns that these symptoms could be caused by a tumor pressing against the stomach, leading to blockages.
In some instances, a pancreatic tumor may cause the gallbladder or liver to enlarge. The American Gastroenterological Association advises that any unusual swelling or masses, particularly under the right side of the ribcage, should prompt medical evaluation.
Finally, fatigue, although a nonspecific symptom, can also be a sign of pancreatic cancer. The American Cancer Society suggests that when fatigue is paired with symptoms like unexplained weight loss or abdominal pain, it should be evaluated as soon as possible.
Recognizing these signs early and seeking medical evaluation could lead to earlier diagnosis, potentially improving survival rates.